Up to now, at least three age-dependant clinical phenotypes have been described for this disease entity, i.e. Neonatal Intrahepatic Cholestasis caused by Citrin Deficiency (NICCD, OMIM#605814) in infants, adult-onset citrullinemia type II (CTLN2, OMIM#603471) in adolescents/adults, and Failure to Thrive and Dyslipidemia caused by Citrin Deficiency (FTTDCD), a novel CD phenotype between NICCD and CTLN2 stage which was proposed very recently [12]–[15]. The gene discussed is SLC25A13; the disease is hyperinsulinemic hypoglycemia, familial, 4.