PGC and gastric cancer: In this case-control study using a Chinese population, we investigated the association of pri-let-7a-1 rs10739971 with gastric cancer risk, and the interaction effects of miRNA-let-7a-1 rs10739971 polymorphism and PGC and ERCC6 polymorphisms in samples of the same group, and discuss its application prospects in gastric cancer and its precancerous diseases.