In the patients with age-related macular degeneration there was on average no significant difference in MPOD between the two visits within the three months of anti-VEGF treatment (visit one: mean MPOD = 0.47±0.1 D.U. and visit 2: mean MPOD = 0.44±0.2 D.U., p = 0.4). This evidence concerns the gene VEGFA and age-related macular degeneration.