Specific TRA2B-related splicing processes have been implicated in human diseases like spinal muscular atrophy (splicing of SMN) [22], [23], [24] and in tauopathies like Alzheimer’s disease and FTDP-17 (splicing of MAPT) [25], [26], [27], [28]. The gene discussed is SMN2; the disease is proximal spinal muscular atrophy.