Eukaryotic initiation factor 4E (eIF4E), which together with eukaryotic initiation factor 4G (eIF4G) and eukaryotic initiation factor 4A (eIF4A) form the cap-binding complex, is frequently overexpressed in human cancer and can cooperate with the Myc oncogene in an experimental lymphoma model [3]. This evidence concerns the gene EIF4E and cancer.