In females, the mRNA level of Tnfsf4 was 3.7 times higher in atherosclerosis-susceptible C57BL/6J mice than in atherosclerosis-resistant C3H/HeJ mice [9], and the Tnfsf4-OX40 signaling is proposed to affect the susceptibility of atherosclerosis by modulating T cell proliferation [9]. The gene discussed is TNFSF4; the disease is atherosclerosis.