In the recessive model, when the NAT2 rs1565684 TT/TC genotypes were used as the reference group, the CC homozygote genotype was associated with an 86% increased risk of ESCC (CC vs. TT/TC: OR = 1.86, 95% CI = 1.04–3.33, p = 0.037) (Table 3). This evidence concerns the gene NAT2 and esophageal squamous cell carcinoma.