In the dominant model, the NAT2 rs1565684 TC/CC variants were not associated with the risk of ESCC, compared with the NAT2 rs1565684 TT genotype (TC/CC vs. TT: OR = 1.20, 95% CI = 0.96–1.51, p = 0.107). The gene discussed is NAT2; the disease is esophageal squamous cell carcinoma.