Furthermore, all three Hox genes located upstream of miR-196b were significantly up-regulated in HD (HOXA10, FDR-adjusted q-value = 1.11e-02; HOXA11, FDR-adjusted q-value = 2.07e-03; HOXA13, FDR-adjusted q-value = 2.24e-02). The gene discussed is HOXA13; the disease is Huntington disease.