Comparison of the progression network with a large scale meta-analysis of MoMLV targets in T-cell lymphomas from various genetic backgrounds [3] showed that the principles of complementation apply where the two germ-line oncogenes are present, as insertions at Myc and Runx family members were massively under-represented in the progression set. The gene discussed is MYC; the disease is T-cell non-Hodgkin lymphoma.