In contrast, HLA-E levels were initially increased in HCMV infected cells (GFPpos, Fig. 8e and 8f), probably because of the viral UL40 protein, but were then reduced as infection prolonged (Fig. 8g and 8h), probably due to the editing of miR-376a(e) which results in the down regulation of HLA-E. Here, HLA-E is linked to infection.