It was also found in the experiment that p65 protein (r = 0.971, P < 0.05), the subunit of NF-κB, and p65 mRNA (r = 0.955, P < 0.05) were both positively correlated with the expression of α-SMA protein in lung Fbs in the process of bleomycin-induced acute lung injury. The gene discussed is ACTA1; the disease is injury.