On the basis of the above, and as there is paucity of a serviceable biomarker of outcome in MDS patients treated with azacitidine, we addressed the prognostic impact of CD25 expression in a cohort of 61 patients with IPSS intermediate-2/high-risk MDS and chronic myelomonocytic leukemia-2 managed between June 2009 to September 2013 at eight Greek institutions in a non-clinical trial setting. Here, IL2RA is linked to myelodysplastic syndrome.