ETS1 and breast cancer: Of particular relevance is the fact that ETS-1 is defined as a candidate breast cancer oncogene involved in the regulation of the expression of genes involved in tumor progression and metastasis (Switzer et al., 2012) and that the expression of ETS-1 correlates with higher incidence of metastasis and poorer prognosis in breast and ovarian carcinoma (Buggy et al., 2004; Furlan et al., 2008; Gilles et al., 1997).