Perhaps the generation of such a stable cell line will be possible only when maspin-NLS will be under a strictly controlled inducible promoter.Anti-proliferative activity of nuclear maspin on MCF-7 cells (Figures 4 and 5) was confirmed on other breast cancer cell lines: SKBR-3 cells and highly invasive MDA-MB-231 cell line (Figure 6). This evidence concerns the gene SERPINB5 and breast carcinoma.