Besides of colon cancer tissues, previous studies have shown that significantly high levels of Cat S have been reported in a range of tumors including glioma[28], astrocytoma[24], lung cancer[40], prostate cancer[41], hepatocellular[27], and pancreatic carcinomas[42], revealing a possible role for this enzyme in tumour growth and progression. The gene discussed is CAT; the disease is Familial prostate cancer.