IGHE and sclerosing cholangitis: However, 2 months after operation, one case (patient No. 1) appeared to have obstructive jaundice, mildly elevated γ-GT, and significant increase in γ-globulin, IgE and IgG, which raised the possibility of coexisting sclerosing cholangitis, and then was treated with prednisone with a dose of 40 mg/day.