Consistent with this argument, a recent report found that tubastatin restored mitochondrial transport in a cell model of amyloid toxicity [42], while another recent study suggested that inhibition of HDAC6 enzymatic activity by tubastatin increases its direct binding to microtubules and possibly enhanced microtubule stability in human breast cancer cells (MCF-7) [43]. Here, HDAC6 is linked to breast carcinoma.