Therefore, next we were prompted to investigate if MBP-primed Th2 cells were capable of suppressing the expression of inflammatory molecules in microglia in the presence of different neurotoxins such as poly-IC (viral encephalopathy), HIV-1-coat protein gp120 (HAD), Amyloid-β (AD) and MPP+(PD). The gene discussed is GOLPH3; the disease is Parkinson disease.