ADIPOQ and obesity due to melanocortin 4 receptor deficiency: Variability at the adiponectin locus associated with obesity and other features of the insulin resistance syndrome has been studies intensively in the last years (Comuzzie et al., 2001; Menzaghi et al., 2007), but a limited number of studies have examined the role of heredity in the regulation of adiponectin among individuals of African heritage (Miljkovic-Gacic et al., 2007).