MAPT and columnar cell hyperplasia of the breast: We therefore studied site-specific tau phosphorylation and found elevated tau phosphorylation at two sites (Thr212 and Ser262) in the cerebral cortex and six sites (Ser199, Thr205, Thr212, Ser214, Thr231, and Ser262) among the eight phosphorylation sites studied in the hippocampus in mice after CCH.