ARNT and myocardial ischemia: Thus, we first verified the success of UCCAO by detecting the levels of hypoxia inducible factor-1β (HIF-1β), TP53-induced glycolysis and apoptosis regulator (TIGAR) and glucose transporters (GLUTs) 1 and 3, because the expression of these proteins increases during cerebral or cardiac ischemia (Watanabe et al., 2009; Kimata et al., 2010; Chan et al., 2011; Iwabuchi and Kawahara, 2011; Yan et al., 2011; Yuan et al., 2011; Hoshino et al., 2012; Wang et al., 2012a,b).