Since transforming growth factor-β (TGF-β) and connective tissue growth factor (CTGF) play a significant role in the progression of renal fibrosis in both clinical and experimental renal disease, we examined the renal expression of TGF-β and CTGF mRNA by real-time RT–PCR on Days 7 and 14. Here, TGFB1 is linked to renal fibrosis.