Transcripts for the lysosomal proteins hexosaminidase subunit A, aspartyl glucosaminidase, cathepsin K, SCARB2/LIMP2 and iduronidase alpha all rose significantly in control, Gaucher disease and Parkinson’s disease with GBA mutation cells after ambroxol treatment (Supplementary Table 3). This evidence concerns the gene SCARB2 and Gaucher disease.