Ettl et al. reported the occurrence of genomic aberrations of the tyrosine kinase receptors EGFR, human epidermal growth factor receptor 2 (HER2), and hepatocyte growth factor (MET) as well as phosphatase and tensin homolog on chromosome 10 (PTEN) in different subtypes of salivary gland carcinomas 25,26, which have a strong impact on overall survival 27. The gene discussed is PTEN; the disease is salivary gland carcinoma.