PDLIM7 and nasopharyngeal carcinoma: In this respect, it has been demonstrated that inhibition of LMP-1 expression by a DNAzyme (Dz1) able to cleave LMP-1 mRNA down-regulates the expression of the catalytic subunit of telomerase (TERT), both at the protein and mRNA levels, and consequently inhibits telomerase activity in LMP1-positive nasopharyngeal carcinoma cells [29].