EGFR and AIDS: Few authors have also proposed involvement of high risk HPVs in the oncogenesis through altered expression of other key molecules involved in tyrosine kinase pathways, in which inverse expressions of epidermal growth factor receptor (EGFR) and its phosphorylated form (pEGFR) have been reported to contribute to the pathogenesis of HIV/AIDS–associated SCCC, and correlates with poor prognosis [25-27].