In subjects with acute ischemic stroke and metabolic syndrome compared to subjects with acute ischemic stroke without metabolic syndrome we observed a more significant positive correlation for age, and gender, between AIX and IL-6 (r = 0.33 vs. r =0.23; p = 0.022), TNF-α (r =0.32 vs. r = 0.26; p = 0.033) and vWF (r = 0.36 vs. r =0.31; p = 0.031) (see Table 3). The gene discussed is VWF; the disease is metabolic syndrome.