It is important to note that this does not seem to be the case in our study, because we did not observe increased mortality in apocynin-treated animals (data not shown) and in the inflammatory response induced by sepsis (as demonstrated by the evaluation of proinflammatory cytokines levels); this outcome may be explained by the low doses used to block NAPDH oxidase in our conditions. This evidence concerns the gene FMO5 and Sepsis.