CD40LG and infection: Although IgM sensitivity appeared to be affected by geographical regions with sensitivities ranging from 38.5% to 93.1% (Table 2), ANOVA test of logistic regression on IgM results indicated that the infection status (p-value < 0.001) and serotype (p-value = 0.044) were the factors that influenced the IgM sensitivity as shown in Table 3.