If KiGE was used instead of Ki67, histological grade and ER, we found that KiGE (HR = 2.0, 95% CI: 1.1-3.6, p = 0.03) and nodal status (p = 0.003, 2-degree of freedom test) were independent long-term prognostic factors for BCM in multivariable analysis. The gene discussed is ESR1; the disease is blue cone monochromacy.