In particular, twelve genes (CCND1, CCNL1, CKAP4, CRABP1, FGF3, GRHL2, MYEOV, PKP4, RAP2B, RPL14, SMAD3, ZNF639) were associated with "Carcinoma, Squamous Cell" and eleven genes (CCND1, CKAP4, CRABP1, EVI1, FGF3, MYEOV, PKP4, RPL14, SMAD3,TMEM16A,ZNf639) were associated with "Esophageal Neoplasms". The gene discussed is GRHL2; the disease is carcinoma.