Among them are CDC42 (cell division control protein), PRKACA (cell signaling), CTNNB1 (cell adhesion), CHP2 (cell proliferation and tumor growth), PIK3R1 (cell proliferation and survival) and KRAS (a known oncogene and potential lung cancer drug target) which play key roles in cell-to-cell signaling, as well as, cell growth, arrest and death. This evidence concerns the gene PIK3R1 and neoplasm.