In the current study we examined the true impact of transvaginal puncture of minimally stimulated polycystic ovaries on the endocrine profile and conclude that the effect is only temporary: serum AMH concentrations had returned to levels before oocyte retrieval within two weeks after IVM-OR and the reduction of androgen levels had disappeared within three months after IVM-OR, at least in the subset of patients who had a follow-up at three months. This evidence concerns the gene AMH and polycystic ovary syndrome.