Once WNT/β-catenin pathway was identified as a pathway that was triggered by WNT5B, we performed correlation study of WNT5B-related WNT/β-catenin pathway target genes in 884 breast tumor samples; Myc was demonstrated a significant correlation with WNT5B (Additional file 1: Figure S4a). The gene discussed is WNT5B; the disease is breast neoplasm.