HIF-1α levels positively correlated with CRP (r = 0.226, P = 0.023), IL-6 (r = 0.316, P<0.001), UKPDS risk score (r = 0.144, P = 0.009), HbA1c (r = 0.242, P<0.001) FBG (r = 0.244, P = 0.029), and CAC scores (r = 0.360, P<0.001), but did not correlate with diabetes duration, age, and LDL (Table 3). The gene discussed is HIF1A; the disease is diabetes mellitus.