SP1 and posterior cortical atrophy: Interestingly, most of transcription factor networks were reported to be related with PCa, such as SP1 [57], c-Myc [58], AR [59], and p53 [60], supporting the hypothesis that the collected genes from systematic annotation of PCa GWAS LD SNPs were putative PCa biomarkers, and therefore provided more informative insights for regulatory systems in PCa, rather than the analysis of SNPs alone.