After enrichment test, we found that 3 of the top 10 networks were significantly associated with PCa, that is "HNF3, IGF-1 receptor, IGF-2 receptor" (p-value = 1.610 × 10-17), "TEF, IGF-1 receptor, IGF-2 receptor (p-value = 3.920 × 10-11)" and "COUP-TF, IGF-1 receptor, IGF-2 receptor (p-value = 1.148 × 10-11)", which greatly raised the feasibility of our method. Here, FOXM1 is linked to posterior cortical atrophy.