CTCF and posterior cortical atrophy: In terms of biological process, we found that some genes of these GO enriched PCa genes have already been proved important in PCa, such as NADH dehydrogenase (NDUF) subcomplexes [52] (NDUFA11, NDUFA13, NDUFA3, NDUFS8, NDUFV1), IGF-2 [58] and CTCF [62] in the cellular regulation process, and SOCS2 [63], HNF1B [64], CCND1 [61], and INS [65] in the metabolic process.