Many translocations have been found with this ALK gene, including EML4:ALK which is responsible for approximately 3-5% of non-small-cell lung cancer(NSCLC) [13], RANBP2:ALK, TPM4:ALK in inflammatory myofibroblastic tumor [24,25], NPM1:ALK, ATIC:ALK, TFG:ALK in anaplastic large cell lymphoma [26-29], and so on. The gene discussed is RANBP2; the disease is anaplastic large cell lymphoma.