The FBN1 gene has been previously associated with various conditions, including MFS, neonatal MFS, Shprintzen-Goldberg syndrome, marfanoid neonatal progeroid syndrome, familial arachnodactyly, ectopia lentis, isolated ascending aortic aneurysm and dissection, aortic root dilatation without dissection, skeletal and skin abnormalities (MASS phenotype), Marfan-like syndromes, autosomal dominant Weill-Marchesani syndrome (WMS), mitral valve prolapse, and sclerodermia. This evidence concerns the gene FBN1 and Shprintzen-Goldberg syndrome.