In addition, the lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), which is predicated to be downregulated in many types of heart disease by the NextBio-Disease Atlas (http://www.nextbio.com/b/search/da.nb), is downregulated upon TNFα stimulation (Additional file1B). The gene discussed is TNF; the disease is heart disorder.