A meta-analysis published in 2004 of 22 population-based prospective studies, including a total of 7068 incident cases of coronary heart disease, found an adjusted odds ratio for the incidence of coronary heart disease of 1.6 (95% confidence interval 1.5 to 1.7) in patients with baseline CRP levels in the top third of the population analysed (approximately ≥2.4 mg/L), compared with patients with baseline CRP levels in the bottom third (approximately 1.0 mg/L) [11]. Here, CRP is linked to coronary artery disorder.