CRP and cardiac hypertrophy: In conclusion, our data suggests that buspirone prevents not only the STZ induced metabolic abnormalities but also cardiovascular complications as evident from the reduction in cholesterol, triglyceride, LDH, CK-MB, CRP, creatinine, urea and collagens levels, and decrease in cardiac hypertrophy and left ventricular hypertrophy which are the initial symptoms of congestive heart failure.