Cks1 has been implicated in development of oral squamous cell carcinoma [131–133], salivary gland tumors [106], esophageal carcinomas [80,134,135], gastric carcinoma [20,136], colorectal carcinoma [108], gall bladder carcinoma [137] and hepatocellular carcinoma [19, 138–142]. This evidence concerns the gene CKS1B and hepatocellular carcinoma.