In accordance with our former studies [4], recent studies of cadmium nephropathy in Japan [5] and in BEN [6], it seemed that alpha 1 microglobulin (A1MG) could be good candidate biomarker of tubular damage in BEN, but there are many conflicting results regarding its superiority to beta 2 microglobulin (B2MG). This evidence concerns the gene AMBP and Balkan nephropathy.