A laboratory examination revealed leukocytosis (white blood cell count [WBC]: 11,900/mm), normocytic normochromic anemia (Hb: 6.1 g/dL), elevation of C-reactive protein (CRP) level (6.1 mg/dL), and renal dysfunction (BUN: 42.6 mg/dL, Cr: 4.04 mg/dL). The gene discussed is CRP; the disease is anemia (phenotype).