Of these, cell death was the most significant due to multiple genes involved in apoptosis, including B-cell CLL/lymphoma 2 (BCL2), B-cell CLL/lymphoma 3 (BCL3), BCL2-like 11 (BCL2L11), BCL2-like 1 (BCL2L1), serine/threonine kinase 24 (STK24), and caspase 9 (CASP9). This evidence concerns the gene BCL3 and B-cell chronic lymphocytic leukemia.