In patients with acute coronary syndrome, the number of peripheral blood Th17 cells, Th17-related cytokines (IL-17, IL-6, and IL-23), and transcription factor (RORγt) levels are significantly increased, and the number of Treg cells, Treg-related cytokines (IL-10 and TGF-β1), and transcription factor (Foxp3) levels in the serum are decreased [39]. This evidence concerns the gene TGFB1 and acute coronary syndrome.