Regulates progressive supranuclear palsy, regulator of the brain-to-body resolution of inflammation, contribute to neurodevelopmental and neuromorphological pathologies, neuronal cell development, regulate synaptic plasticity, neuronal maturation, regulates basal and activity-induced neurite outgrowth, regulates recognition memory and synaptic plasticity, regulates Circadian Clock. The gene discussed is CLOCK; the disease is progressive supranuclear palsy.