CDH3 and breast cancer: Thus, to further explore the role of α6 integrin and its partner, β4 integrin, in the functional properties mediated by P-cadherin, we analyzed the cell-laminin adhesion capacity and the MFE of a breast cancer cell line constitutively overexpressing P-cadherin (MCF7/AZ.P-cad) and compared these properties with control cells, which have low levels of P-cadherin (MCF7/AZ.mock).