From the Human Tumor Metastasis RT-PCR array with ATAD2 siRNA-treated cells, we identified APC, ITGB3, FXYD5, ITGA7 and CTNNA1 (α-catenin), which are related to cell adhesion; among these, the expression of APC and CTNNA1 changed by at least 3-fold. The gene discussed is APC; the disease is neoplasm.