CFTR and Obstructive azoospermia: CBAVD, a CF-related disorder (OMIM 219700) [13], is an important congenital cause of male infertility and obstructive azoospermia, which correlated closely with specific CFTR mutations in western populations, mainly R117H, delF508, and 5T, which are distributed differently in different subgroups of people [2].