As shown in table 1, saliva CRP levels between the three groups including: pantients with periodontitis, gingivitis and control group, were statistically different (P= 0.045 .(However using Mann-Whitney test, statistically significant result for CRP level was obtained only when the perio-dontitis group was compared with the control group (P=0.01) (Fig. 1). This evidence concerns the gene CRP and periodontitis.